Python Tools for Visual Studio - Beta

-Advanced editing, Intellisense, browsing, “Find all”, REPL, …
-Supports CPython and IronPython
-Local & Cluster/remote debugging
-Profiling with multiple views
-Interactive parallel computing via integrated IPython REPL
-Support for HPC clusters and MPI, including debugging support 1
-NumPy & SciPy for .Net
-Support for Cloud Computing (soon)
-Support for Dryad (large scale, data-intensive parallel programming) (soon)
-Free & Open Source (Apache 2.0)

http://pytools.codeplex.com/